Wnt signaling pathway - Wikipedia
The three best characterized Wnt signaling pathways are the canonical Wnt pathway, the noncanonical planar cell polarity pathway, and the noncanonical Wnt/calcium pathway. As their names suggest, these pathways belong to one of two categories: canonical or noncanonical.
Wnt signal transduction pathways - PMC - PubMed Central (PMC)
The Wnt signaling pathway is an ancient and evolutionarily conserved pathway that regulates crucial aspects of cell fate determination, cell migration, cell polarity, neural patterning and organogenesis during embryonic development. The Wnts are ...
Wnt/β-catenin signalling: function, biological mechanisms, …
Jan 3, 2022 · The canonical Wnt pathway mainly controls cell proliferation, whereas the noncanonical Wnt pathways regulate cell polarity and migration, and the two main pathways form a network of mutual...
Wnt/β-catenin signaling: components, mechanisms, and diseases
A critical and most studied Wnt pathway is canonical Wnt signaling, which functions by regulating the amount of the transcriptional co-activator β-catenin that controls key developmental gene expression programs.
Wnt/β-catenin signalling: function, biological mechanisms, and ...
The canonical Wnt pathway mainly controls cell proliferation, whereas the noncanonical Wnt pathways regulate cell polarity and migration, and the two main pathways form a network of mutual regulation. Wnt signalling plays an important …
Wnt signaling pathway: A comprehensive review - PubMed
Wnt signaling is an evolutionary cell-to-cell coordination mechanism and it is highly critical for a variety of physiological processes of an organism's body, including stem cell regeneration, proliferation, division, migration, polarity of a cell, determining fate of the cell and specification of n …
Wnt/β-Catenin Signaling and Disease - Cell Press
In this Review, we provide an update of the core Wnt/β-catenin signaling pathway, discuss how its various components contribute to disease, and pose outstanding questions to be addressed in the future.
Wnt Signaling Pathway - an overview | ScienceDirect Topics
The Wnt signaling pathway is classified into two major types: (a) Canonical or β-catenin-dependent pathway, and (b) Non-canonical or β-catenin-independent pathway. The Wnt pathway is triggered by a set of conserved secreted glycoproteins known as Wnts, which are expressed widely across all metazoan species.
The Wnt Pathway: From Signaling Mechanisms to Synthetic …
Jun 21, 2022 · We review advances in our understanding of this key pathway, from Wnt protein production and secretion to relay of the signal in the cytoplasm of the receiving cell. We discuss the evolutionary history of this pathway as well as endogenous and …
Everything You Would Like to Know About Wnt Signaling
Wnts are secreted glycoproteins that bind to specific cell surface receptors and activate signaling in a mostly paracrine fashion. Wnts trigger distinct intracellular pathways, including canonical signaling through β-catenin and noncanonical planar cell polarity (PCP) and Ca 2+ signaling (Fig. 1).