Pellicon® Single-Pass Tangential Flow Filtration - Merck
Oct 16, 2018 · Intensify chromatography and filtration steps; Run connected or continuous processes
Cogent® Process-Scale Tangential Flow Filtration System - Merck
A fully-automated, configurable, TFF system suited for manufacturing of biopharmaceuticals and cGMP process-scale applications. The fully automated Cogent ® TFF system is designed to separate and purify monoclonal antibodies, vaccines, plasma, and therapeutic proteins.
The Cogent® µScale TFF system is designed to enable scalable tangential flow filtration (TFF), ultrafiltration (UF) concentration and diafiltration (DF) process development in laboratory settings.
Merck Introduces New Single-use Technologies to Advance …
Apr 17, 2018 · · Pellicon ® Capsule with Ultracel ® Membrane, a first-of-its-kind single-use tangential flow filtration device that advances flexible manufacturing. · Millipak ® Final Fill Filter, for high-value, small-volume processing. · Mobius ® Power MIX 2,500-Litre and 3,000-Litre large-scale single-use mixers.
Optimization & Process Simulation for Ultrafiltration - Merck
Tangential Flow Filtration: Fluid is pumped tangentially along the surface of the membrane. An applied pressure forces a portion of the fluid through the membrane to the filtrate side and the remainder recirculates on the upstream side of the filter.
Tangential Flow Filtration Devices - MilliporeSigma
The optimum tangential flow filtration devices for monoclonal antibodies and other therapeutic proteins. Data Sheet: Pellicon ® 3 Cassettes with Biomax ® Membrane The device of choice for applications requiring higher yield, fast processing, and exceptional chemical resistance
Our broad selection of tangential flow filters enables bench-to-process scale single-pass filtration of mAbs, recombinant proteins, plasma, albumin, hormones, growth factors, vaccines, and viruses. Biomax® membrane The high flux and high retention properties of Biomax® membranes result in faster processing with high yields.
Merck KGaA of Darmstadt, Germany, today introduced single-pass tangential flow filtration (TFF) with Pellicon® cassettes, an enhanced application of EMD Millipore’s existing TFF technology that allows concentration of process streams without the recirculation required in traditional TFF.
Tangential flow filtration
Use tangential flow filtration for feeds that contain high proportions of solids with small particle sizes where the permeate is the molecule of interest. This is because solid materials can speedily clog the filter surfaces during normal flow filtration.
Membrane is the first-of-its-kind single-use tangential flow filtration capsule for bioprocessing of antibody-drug conjugates and monoclonal antibodies. The capsule combines fast, user-friendly and efficient processing of biologics with reliable performance and …