Establishment of a rat model of myocardial infarction with a high ...
The most common rat model of myocardial infarction (MI) is by ligation of left anterior descending (LAD) coronary artery but it is associated with high mortality and large variations in the infarct …
A rodent model of myocardial infarction for testing the efficacy of ...
Nov 9, 2006 · In this protocol, we describe a step-by-step methodology for creating an ischemia-reperfusion rat model of MI, followed by therapeutic injections of MSCs delivered …
Ischemic Model of Heart Failure in Rats and Mice
Jul 10, 2018 · In the present protocol, we describe the materials necessary for the procedure, key steps of the LCA ligation, triphenyl tetrazolium chloride (TTC) staining, and calculation of …
Methods for Histological Characterization of Cryo-Induced …
This quantitative histological study of cryo-induced MI in a rat model can aid others attempting to optimize MI models in rats via cryo-injury, to study cardiac disease progression, and to aid in …
Ischemic Model of Heart Failure in Rats and Mice - PubMed
In the present protocol, we describe the materials necessary for the procedure, key steps of the LCA ligation, triphenyl tetrazolium chloride (TTC) staining, and calculation of myocardial …
Quantitative Analysis of Acute Myocardial Infarct in Rat Hearts …
Jul 1, 2002 · Results: Left and right ventricular myocardium in control rats was shown clearly, with uniform 99m Tc-sestamibi distribution and 100% TTC staining for viable myocardium. Nine of …
Coronary artery ligation is widely used for myocardial infarction (MI) induction in rats but produces a large variation in infarct size – a major determinant of mortality. Accurate control of infarct …
A New Model of Heart Failure Post-Myocardial Infarction in the Rat
Jun 10, 2021 · This new model of HF post-MI in the rat is vital for studying the potential mechanisms of MI and HF. This new method can be used to develop the new drug for …
Histological Quantification of Chronic Myocardial Infarct in Rats
Dec 11, 2016 · Fibrotic tissue can be accurately assessed in a chronic MI rat model using systematic sampling of the harvested heart and image analyses of trichromatic-stained …
Automated Quantification of Myocardial Salvage in a Rat Model …
Aug 21, 2014 · Current “gold‐standard” methods perfuse the heart with Evan's Blue and stain with triphenyl tetrazolium chloride (TTC), requiring manual slicing and analysis. We aimed to …