Distribution and spread of colonic lesions in shigellosis: a ...
These findings indicate that the rectosigmoid is the most frequently and most severely affected area of the colon in shigellosis and suggest that during the course of shigella infection, colonic lesions extend in a proximal direction.
Pathology Outlines - Shigella
Apr 17, 2023 · Negative for granuloma or viral cytopathic effects. The histologic findings are most in keeping with an infectious colitis. Inflammatory bowel disease is less likely. Correlation with clinical history, microbiological and serologic findings is recommended.
The colon in shigellosis: serial colonoscopic appearances in Shigella ...
Six abnormal colonoscopic appearances were documented, namely mucosal edema, ulcers, friability, punctate spots, erythematous areas and luminal exudate. Mucosal edema was the dominant finding in the first week of the disease. Star-shaped mucosal ulcers and friability were observed in the 2nd and 3rd weeks of the disease.
Shigellosis - StatPearls - NCBI Bookshelf
Feb 26, 2024 · After leaving the stomach, shigellae multiply in the small intestine and enter the colon. In the colon, this species secretes virulence factors that cause extreme inflammation and mediate enterotoxic effects to allow colonization and invasion of the colonic epithelium.
Infectious Colitis - StatPearls - NCBI Bookshelf
Sep 26, 2022 · Colonic infection by bacteria, viruses, or parasites results in an inflammatory type of diarrhea, accounting for most cases presenting with acute diarrhea. These patients present with purulent, bloody, and mucoid loose bowel motions, fever, tenesmus, and abdominal pain. Common bacteria causing bacterial colitis include Campylobacter jejuni (C. jejuni), Salmonella, Shigella, Escherichia coli (E ...
Bacterial Infections of the Colon - Types and Treatment - iCliniq
May 5, 2023 · Shigella: Shigella is a gram-negative enteric group of organisms that causes gastrointestinal illnesses ranging from mild diarrhea to severe dysentery.
Shigellosis - The Lancet
Shigellosis is a clinical syndrome caused by invasion of the epithelium lining the terminal ileum, colon, and rectum by Shigella species. Although infections occur globally, and in people of all ages, endemic infections among children aged 1–4 years living in low-income and middle-income settings constitute most of the disease burden.
Bioimage analysis of Shigella infection reveals targeting of …
In this work, we present a novel approach for the investigation of host–pathogen processes based on medium-throughput 3D fluorescence imaging. The guinea pig model for Shigella flexneri invasion of the colonic mucosa was used to monitor the infectious process over time with GFP-expressing S. flexneri.
Shigella Infections | Red Book: 2021–2024 Report of the Committee …
Shigella species primarily infect the large intestine, causing clinical manifestations that range from watery or loose stools with minimal or no constitutional symptoms to more severe symptoms, including high fever, abdominal cramps or tenderness, tenesmus, …
Clinical Overview of Shigellosis | Shigella - Shigellosis | CDC
Mar 18, 2024 · Healthcare providers can order laboratory tests to identify Shigella germs in the stool of an infected person. Characterizing isolates can lead to more accurate diagnoses, targeted treatment (when needed), improved patient outcomes, and earlier detection of outbreaks.