Jul 7, 2019 · am and IV diazepam are successful at stopping seizures within five minutes. There is level B evidence that IM midazolam, intranasal midazolam, recta. diazepam, and buccal midazolam are most likely efficacious at stopping SE. There is inadequate evidence to support the use of sublingual, rectal, and intranasal lorazepam, valpr.