The human cell in secreted proteins - The Human Protein Atlas
Secreted proteins, together forming the secretome, can be defined as proteins that are actively transported out of the cell. In humans, cells such as endocrine cells and B-lymphocytes are …
Regulation of protein secretion through chemical regulation of
Mar 14, 2022 · Protein secretion is an important cellular mechanism to translocate soluble or membrane-bound proteins in order to respond to the changes in the cellular environment or …
The human secretome | Science Signaling - AAAS
Nov 26, 2019 · Here, we present a comprehensive analysis of proteins predicted to be secreted in human cells, which provides information about their final localization in the human body, …
Protein Secretion - an overview | ScienceDirect Topics
Protein secretion (Fig. 1) is one of the most fundamental biological processes in prokaryotes as the secreted proteins are involved in the regulation of numerous cellular functions (e.g., …
SEPDB: a database of secreted proteins - Oxford Academic
Feb 12, 2024 · Enter secreted protein database (SEPDB), an integrated secretory proteomics database offering human, mouse and rat secretory proteomics datasets collected from serum, …
Through the back door: Unconventional protein secretion
Dec 1, 2020 · Proteins, such as histones and FABP4, are sorted from the cytosol in membrane-bounded organelles such as MVBs or amphisomes, and are then secreted as free proteins. …
Revealing the secretome - Nature Methods
Nov 3, 2021 · Here, biotinylated proteins that entered the blood plasma were captured, identified by mass spectrometry and used to generate proteomic atlases. Their results confirmed certain …
Protein Secretion - an overview | ScienceDirect Topics
Secreted proteins include signaling molecules such as hormones, cytokines, and chemokines, as well as extracellular matrix proteins such as collagens, which provide structural and …
Secreted proteins as a fundamental source for biomarker discovery
The proteins secreted by various cells (the secretomes) are a potential rich source of biomarkers since they reflect various states of the cells at real time and at given conditions. To have …
Cell type-selective secretome profiling in vivo - Nature
Nov 16, 2020 · Our secretome dataset validates known cell type–protein pairs, reveals secreted polypeptides that distinguish between cell types and identifies new cellular sources for …
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