The FGF family: biology, pathophysiology and therapy - PMC
The family of fibroblast growth factors (FGFs) regulates a plethora of developmental processes, including brain patterning, branching morphogenesis and limb development.
Fibroblast growth factor - Wikipedia
Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by macrophages; they are involved in a wide variety of processes, most notably as crucial elements for normal development in animal cells. Any irregularities in their function lead …
The Fibroblast Growth Factor signaling pathway - PMC
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF receptors (FGFRs). Interaction of FGF ligands with their signaling ...
Fibroblast Growth Factors: Biology, Function, and Application for ...
Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation.
The FGF family: biology, pathophysiology and therapy
Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are...
The Fibroblast Growth Factor signaling pathway - PubMed
Members of the FGF family function in the earliest stages of embryonic development and during organogenesis to maintain progenitor cells and mediate their growth, differentiation, survival, and patterning.
The FGF family: biology, pathophysiology and therapy - PubMed
The family of fibroblast growth factors (FGFs) regulates a plethora of developmental processes, including brain patterning, branching morphogenesis and limb development.
Fibroblast Growth Factors - Madame Curie Bioscience Database
FGFs and their receptors (FGFRs) have been implicated in many aspects of neuronal development, where they promote proliferation, differentiation and axonal branching.
Fibroblast growth factors | Genome Biology | Full Text - BioMed …
Feb 3, 2001 · Fibroblast growth factors (FGFs) make up a large family of polypeptide growth factors that are found in organisms ranging from nematodes to humans. In vertebrates, the 22 members of the FGF family range in molecular mass from 17 …
Fibroblast Growth Factor - an overview | ScienceDirect Topics
Fibroblast growth factor (FGF), another growth factor in IPF, also signals through a nintedanib-sensitive receptor tyrosine kinase. 108 FGFs represent a family of 22 molecules, and there are a number of reports suggesting that some FGF members are profibrotic, whereas others may be …