B cell - Wikipedia
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. [1] They function in the humoral immunity component of the adaptive immune system. [1] B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors. [2]
B Cells and Antibodies - Molecular Biology of the Cell - NCBI …
The first antibodies made by a newly formed B cell are not secreted. Instead, they are inserted into the plasma membrane, where they serve as receptors for antigen. Each B cell has approximately 10 5 such receptors in its plasma membrane.
Cell membrane | Definition, Function, & Structure | Britannica
Nov 18, 2024 · Cell membrane, thin membrane that surrounds every living cell. The cell membrane functions as a barrier, keeping cell constituents in and unwanted substances out, and as a gate, allowing transport into the cell of essential nutrients and movement from the …
B Cells: Structure, Activation, and Memory Formation
Oct 19, 2024 · The cell membrane of B cells is embedded with proteins that play roles in immune response. Among these are the B cell receptors (BCRs), which are membrane-bound immunoglobulins essential for the recognition of antigens.
Cell Membranes - The Cell - NCBI Bookshelf - National Center for ...
The structure and function of cells are critically dependent on membranes, which not only separate the interior of the cell from its environment but also define the internal compartments of eukaryotic cells, including the nucleus and cytoplasmic organelles.
B cell responses to membrane-presented antigens require the
Sep 26, 2023 · We found that human B cell responses to membrane-presented antigens required the function of Piezo1, a plasma membrane mechanosensitive cation channel. Simply making contact with a glass probe induced calcium (Ca 2+) fluxes in B cells that were blocked by the Piezo1 inhibitor GsMTx4.
B cell responses – Cell interaction dynamics and decisions
Here we review current understanding of how B cell responses are initiated, the different paths to generate short- and long-lived plasma cells, germinal center cells, and memory cells, and how each path impacts antibody diversity, selectivity and affinity.
Cell membrane - Wikipedia
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).
How B cells capture, process and present antigens: a crucial role …
Jun 25, 2013 · In this Review, we discuss membrane trafficking and the associated molecular mechanisms that are involved in antigen extraction and processing at the B cell synapse, and we highlight how B...
The human immune cells - b-cells - The Human Protein Atlas
They express B cell receptors on their surface that allow them to bind specific antigens, and function in the humoral immunity component of the adaptive immune system by secreting antibodies. Additionally, B cells are classical antigen-presenting cells …