Stem cells | MIT News | Massachusetts Institute of Technology
Nov 15, 2023 · In pursuit of the elusive stem cell. New MIT initiative delves into the biology of stem cells and cancer stem cells, seeks ways to identify, purify, and propagate them. October 15, 2018. Read full story →
What can super-healing species teach us about regeneration?
Feb 21, 2024 · Now an assistant professor of orthopedic surgery and stem cell biology and regenerative medicine at the Keck School of Medicine of the University of Southern California (USC), Almada studies the mechanics of how stem cells rebuild tissues after trauma and how stem cell principles are dysregulated and drive conditions like degenerative disease ...
Scientists develop a low-cost device to make cell therapy safer
Feb 7, 2024 · In cell therapy, clinicians create what are known as induced pluripotent stem cells by reprogramming some skin or blood cells taken from a patient. To treat a spinal cord injury, they would coax these pluripotent stem cells to become progenitor cells, which are destined to differentiate into spinal cord cells.
For stem cells, bigger doesn’t mean better - MIT News
Nov 12, 2021 · Blood stem cells from those mice remained small and were able to build blood cells like young stem cells even in mice 3 years of age — an old age for a mouse. Rapamycin, a drug that can inhibit cell growth, is now used to treat some cancers and to prevent organ transplant rejection, and has raised interest for its ability to extend lifespan ...
Blood cell family trees trace how production changes with aging
Jan 31, 2024 · Each one of these lineages is called a clonal group. Researchers have had various hypotheses about how clonal groups work: Perhaps they are interchangeable, with each stem cell producing equivalent numbers and types of blood cells. Perhaps they are specialized, with one stem cell producing red blood cells, and another producing white blood cells.
Study reveals the benefits and downside of fasting | MIT News ...
Aug 21, 2024 · In their new study, the researchers found that stem cell regeneration is suppressed during fasting but then surges during the refeeding period. The researchers followed three groups of mice — one that fasted for 24 hours, another one that fasted for 24 hours and then was allowed to eat whatever they wanted during a 24-hour refeeding period ...
Noninvasive technique reveals how cells’ gene expression ... - MIT …
Jan 10, 2024 · The researchers tested their Raman2RNA algorithm by tracking mouse embryonic stem cells as they differentiated into different cell types. They took Raman images of the cells four times a day for three days, and used their computational model to predict the corresponding RNA expression profiles of each cell, which they confirmed by comparing it ...
Scientists create embryonic stem cells without destroying ... - MIT …
Jun 6, 2007 · Somatic cell nuclear transfer ("therapeutic cloning") offers the hope of one day creating customized embryonic stem cells with a patient's own DNA. In this process, an individual's DNA would be placed into an egg, resulting in a blastocyst that houses a supply of stem cells. But to access these cells, researchers must destroy a viable embryo.
Fasting boosts stem cells’ regenerative capacity - MIT News
May 3, 2018 · Age-related declines in stem cell function can be reversed by a 24-hour fast, according to a new study from MIT. Biologists found fasting dramatically improves stem cells’ ability to regenerate, in both aged and young mice.
Study links certain metabolites to stem cell function in the ... - MIT …
Aug 22, 2019 · When the researchers fed the mice a high-sugar diet, they saw the opposite effect: Ketone production and stem cell function both declined. Stem cell function. The study helps to answer some questions raised by Yilmaz’ previous work showing that both fasting and high-fat diets enhance intestinal stem cell function. The new findings suggest ...