Pyrrole - Wikipedia
Pyrrole is a 5-membered aromatic heterocycle, like furan and thiophene. Unlike furan and thiophene, it has a dipole in which the positive end lies on the side of the heteroatom, with a dipole moment of 1.58 D. In CDCl 3, it has chemical shifts at 6.68 (H2, H5) and 6.22 (H3, H4).
Pyrrole - an overview | ScienceDirect Topics
Pyrrole is defined as an electron-rich heteroaromatic molecule with a five-membered ring containing one nitrogen and four carbon atoms. It has coordinating ability with metals, leading to the formation of various metal complexes with significant functions in nature and in synthetic catalytic systems.
Pyridine and Pyrrole - Chemistry LibreTexts
Pyrrole is a five-membered heterocyclic ring which has 5 p orbitals and six pi electrons contributing to its aromaticity. Each carbon in pyrrole contributes one p orbital and pi electron. The nitrogen in pyrrole contributes two pi electrons by becoming sp 2 hybridized and placing its lone pair electrons into a p orbital.
Pyrrole | Aromatic, Heterocyclic, Nitrogen-Containing | Britannica
pyrrole, any of a class of organic compounds of the heterocyclic series characterized by a ring structure composed of four carbon atoms and one nitrogen atom. The simplest member of the pyrrole family is pyrrole itself, a compound with molecular formula C 4 H 5 N.
15.5: Aromatic Heterocycles - Pyridine and Pyrrole - Chemistry …
Sep 30, 2024 · Pyrrole (spelled with two r’s and one l) and imidazole are five-membered heterocycles, yet both have six π electrons and are aromatic. In pyrrole, each of the four sp 2 -hybridized carbons contributes one \(\pi\) electron and the sp 2 -hybridized nitrogen atom contributes the two from its lone pair, which occupies a p orbital (Figure ...
Pyrroles - Chemistry Online
Apr 22, 2024 · Pyrroles are 5-membered heterocyclic aromatic compounds with one nitrogen atom and 4 carbons in a pentagonal ring. Apart from its interest as an aromatic system, the pyrrole is biologically important because its structure is part of the heme group, chlorophyll and other natural products related to vitamin B12 and bile pigments.
Pyrrole: An insight into recent pharmacological advances with structure ...
Sep 5, 2018 · Pyrrole is a heterocyclic aromatic five membered multiple pharmacophoric template. The name pyrrole came from the Greek word ‘pyrrols’ means fiery from the reaction. Pyrroles exhibit lower basicity due to delocalization of lone pair of …
Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics ...
Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of activities. The combination of different pharmacophores in a pyrrole ring system has led to the formation of more active compounds.
Pyrrole - an overview | ScienceDirect Topics
May 3, 2005 · Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for the generation of library of enormous lead molecules. Owing to its vast pharmacological profile, pyrrole and its analogues have drawn much attention of the researchers/chemists round the globe to be explored exhaustively for the benefit of mankind.
Pyrrole: A Decisive Scaffold for the Development of ... - Chemistry …
Nov 5, 2023 · Pyrrole is a heterocyclic compound, which finds application in various diseases. In this review, we list the natural and synthetic sources of pyrrole, along with various methods for its synthesis.
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