Pathophysiology | Meningitis - U.OSU
Pathophysiology. Meningitis is a disease process where the protective layers that cover the brain and spinal cord become inflamed. Meningitis can be infectious or it can be caused by injury, cancer, and other noninfectious causes. Infectious meningitis can be caused by a bacterial, viral, or fungal infection.
Pathophysiology of Bacterial Meningitis: Mechanism(s) of …
Dec 1, 2002 · In this brief review, we highlight recent epidemiologic trends in bacterial meningitis worldwide and consider the current concepts of the pathogenesis and pathophysiology of this syndrome with an emphasis on the identification of promising targets for adjunctive therapy.
Overview of Meningitis - Neurologic Disorders - Merck Manual ...
Meningitis is inflammation of the meninges and subarachnoid space. It may result from infections, other disorders, or reactions to medications. Severity and acuity vary. Findings typically include headache, fever, and nuchal rigidity. Diagnosis is by cerebrospinal fluid (CSF) analysis.
Meningitis: Practice Essentials, Background, Pathophysiology - Medscape
Oct 24, 2024 · Advancements in understanding the pathophysiology of meningitis have shed light on the crucial roles of various cytokines (eg, tumor necrosis factor alpha [TNF-α] and interleukin [IL]-1),...
Meningitis – McMaster Pathophysiology Review
In bacterial meningitis, glucose transport from the blood into the CSF is impaired; inflammation of the meninges leads to decreased glucose receptor expression. There is also increased anaerobic glycolysis by leukocytes and brain cells.
meningitis. Explain the terms used in the description of CNS infections patterns. Understand the pathology of acute bacterial and tuberculous meningitis and the information that can be obtained from investigation of cerebrospinal fluid in suspected meningitis.
Meningitis - Physiopedia
Meningitis is defined as inflammation of the meninges. The meninges are the three membranes (the dura mater, arachnoid mater, and pia mater) that line the vertebral canal and skull enclosing the brain and spinal cord (encephalitis is inflammation of the brain itself).
Acute Bacterial Meningitis - Neurologic Disorders - Merck …
Jun 26, 2018 · Acute Bacterial Meningitis - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
Pathology Outlines - Meningitis - bacterial
Aug 1, 2014 · Streptococcus - dilated cerebral veins associated with the thick purulent exudate within the leptomeninges.
Pathogenesis and pathophysiology of bacterial meningitis
Most cases of bacterial meningitis begin with host acquisition of a new organism by nasopharyngeal colonization followed by systemic invasion and development of a high-grade bacteremia. Bacterial encapsulation contributes to this bacteremia by inhibiting neutrophil phagocytosis and resisting classic complement-mediated bactericidal activity.