Biomolecular condensates: organizers of cellular biochemistry
Feb 22, 2017 · Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack surrounding membranes but function to concentrate proteins and nucleic acids.
A framework for understanding functions of biomolecular condensates …
Biomolecular condensates are found throughout eukaryotic cells, in the nucleus, cytoplasm and on various membranes. They are also found across the biological spectrum, organizing molecules that act in processes ranging from RNA metabolism to signaling to gene regulation.
Biophysics of biomolecular condensates - PMC
The formation of biomolecular condensates has emerged as a new biophysical principle for subcellular compartmentalization within cells to facilitate the spatiotemporal regulation of a multitude of complex biomolecular reactions.
Higher-order organization of biomolecular condensates - PMC
In this review, we have focused on how and why complex biomolecular condensates adopt specific internal organization and catalogue the condensate architectures described thus far in the literature.
A framework for understanding the functions of biomolecular condensates ...
Nov 9, 2020 · Biomolecular condensates are found throughout eukaryotic cells, including in the nucleus, in the cytoplasm and on membranes. They are also implicated in a wide range of cellular functions,...
Biomolecular condensates: Formation mechanisms, biological …
Feb 28, 2023 · In this review, we summarized the current understanding of biomolecular condensates and the molecular mechanisms of their formation. Moreover, we reviewed the functions of condensates and therapeutic targets for diseases.
Biomolecular condensates at the nexus of cellular stress, protein ...
Jan 28, 2021 · Biomolecular condensates are membraneless intracellular assemblies that often form via liquid−liquid phase separation and have the ability to concentrate biopolymers.
Biomolecular condensates: organizers of cellular biochemistry
Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack surrounding membranes but function to concentrate proteins and nucleic acids. These condensates are involved in diverse processes, including RNA metabolism, ribosome biogenesis, the DNA damage response and signal tr …
Biomolecular Condensates: Structure, Functions, Methods of …
Mar 8, 2024 · The term “biomolecular condensates” is used to describe membraneless compartments in eukaryotic cells, accumulating proteins and nucleic acids. Biomolecular condensates are formed as a result of liquid–liquid phase separation (LLPS).
Biomolecular condensates regulate cellular electrochemical …
Sep 10, 2024 · Our work reveals the biochemical functions of condensates, which extend beyond the functions of biomolecules driving and participating in condensate formation, and uncovers a role of condensates in regulating global cellular physiology.
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