FOOD ALLERGY & ANAPHYLAXIS EMERGENCY CARE PLAN HOW TO USE AUVI-Q® (EPINEPHRINE INJECTION, USP), KALEO 1. Remove Auvi-Q from the outer case. 2. Pull off red safety guard. 3. Place black end of Auvi-Q against the middle of the outer thigh. 4. Press firmly, and hold in place for 5 seconds. 5.