This important study reveals a critical role of the transcription factor NR2F2 in mouse fetal Leydig cell (FLC) differentiation. With elegantly carried out experiments, the authors provide compelling ...

Cell competition in epithelial tissue eliminates transformed cells expressing activated oncoproteins to maintain epithelial homeostasis. Although the process is now understood to be of mechanochemical ...

Researchers at the University of Chicago have captured complete images of adhesion G protein-coupled receptors and an ...

Researchers at the University of Chicago have successfully captured detailed images of adhesion G protein-coupled receptors, ...

Nelson Aguilar is an LA-based tech how-to writer and graduate of UCLA. With more than a decade of experience, he covers Apple and Google and writes on iPhone and Android features, privacy and ...

Proteins are the molecular building blocks and engines of the cell, and are involved in practically all life processes. Researchers at the Max Planck Institute of Biochemistry investigate the ...

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with each ...

Their first study, published in Nature Communications, highlights Rasip1's essential function at the adhesion sites between ...

New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with ...

Furthermore, they found that contraction forces are essential drivers of cell interactions, enabling the continuous vascular lumen formation. They observed that this adhesion site is transformed ...