A team of researchers designed AI model capable of generating new proteins, trained on a simulation of 500 million years of ...

ALE.P02 has a potentially first-in-class tubulin inhibitor payload ... that aims to restore the function of the protein UNC13A, which is thought to play a role in 97% of genetic and sporadic ...

Just like your body has a skeleton, every cell in your body has a skeleton—a cytoskeleton to be precise. This provides cells with mechanical resilience, as well as assisting with cell division. To ...

(D) A model depicting the function of Arp2/3-mediated branched actin polymerization ... 2020) (1:1000), and rabbit anti-β- Tubulin (1:1000; Cell Signaling Technologies; 2146). We thank Dr. Eric Olson ...

Structural damage was highlighted in the AF group by fragmentation of the proteins actin, desmin, and tubulin. García et al 37 used 2 ... focusing on those that can be grouped by function only. As is ...

Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re ...

Importantly, MTCH2 knockout cells showed an increase in mitochondrial oxidative function, which may explain the higher energy demand. Interestingly, this imbalance in energy metabolism and reductive ...

Dysregulated functions of E3 ubiquitin ligases have been linked to many diseases, including T2DM and NAFLD, making them potential targets for drug development. The potential of developing therapeutic ...

Department of Chemical Sciences and Center for Advanced Functional Materials, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur 741246, West Bengal, India Institute for ...

Beta-tubulin (TA-10) was purchased from ZSGB-BIO (Wuxi, China). Lamin B1 Polyclonal Antibody (AP6001) was obtained from Bioworld Technology, Inc. (Shanghai, China). iNOS Polyclonal antibody ...