Protein engineering enables the creation of tailor-made proteins ... Among the latter, one such class of therapeutic molecules is the immune mobilizing monoclonal T-cell receptor (TCR) against cancer ...

Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei all at the same time. The method, called ChIP–DIP (Chromatin ...

The study published today in the journal Cell could lead to more personalized therapies that improve cancer patients’ survival. The researchers identified a protein called YTHDF2 that plays a ...

Adhesion G protein-coupled ... embedded in the cell surface. The different positions and movements of the extracellular region appear to be an important way to activate the receptor.

The study published today in the journal Cell could lead to more personalized therapies that improve cancer patients' survival. The researchers identified a protein called YTHDF2 that plays a ...

A protein called the androgen receptor normally functions to guide the development of the prostate—signaling the cells to stop growing, act as normal prostate cells and maintain a healthy state.

To do that, they developed a polymer coating that integrates with the bacterial cell membrane and chemically modified cell membranes with the catalytic polymers. “We took a common industrial ...

Tests were performed using at least two different protein preparations of each antigen, each experiment included 5-8 technical replicates, which were averaged. NF-ĸB pathway activation and ANA1 cells ...

aCollege of Animal Science and Technology, Foshan University, Foshan, Guangdong, 528231, China bCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, ...

This important work advances our understanding of CHMP5's role in regulating osteogenesis through its impact on cellular senescence. The evidence supporting the conclusion is mostly convincing, ...

One such synthetic receptor is the synNotch receptor, which can be tailored to sense specific ligands displayed on the surface of target cells. With this study, we aimed at developing a novel ...