Can we predict that natural selection will weed out genetic disease over time? Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated ...

Sickle cell anemia refers to a group of genetic blood disorders that affect a person’s levels of hemoglobin, the protein in red blood cells that transports oxygen. Sickle cell anemia causes a ...

More than 500,000 babies were tested for sickle cell disease in Catalonia’s newborn screening program, with 160 cases ...

A once-groundbreaking sickle cell disease drug — at the center of a $5.4 billion acquisition two years ago — is the subject ...

Pediatric patients with sickle cell anemia and a history of abnormal cerebral artery velocities had reduced hospitalizations ...

The UAB Comprehensive Sickle Cell Center brings together scholars and researchers working in the forefront of basic, translational and clinical research, with the overarching goals to discover new ...

Only a few patients have undergone an intensive gene therapy cure for sickle cell disease since it was approved by the FDA due to it's high cost and limited access. NBC News' Yamiche Alcindor spoke ...

Living with Sickle Cell Disease means that every treatment comes with its own side effects. Today, we will focus on the dangers of blood exchange or transfusion and the risk of iron overload.

At 9 months of age he appeared pale. Anemia was found, and electrophoresis established the diagnosis of sickle-cell disease. Both parents had hemoglobin-AS pattern on electrophoresis but were ...

The quality of life of patients with sickle cell anemia is severely compromised similar to or even worse than patients with other chronic diseases such as arthritis. Patients who responded to ...

This phase 1–2, randomised, double-blind, placebo-controlled trial enrolled 130 patients aged 18 or older with confirmed ...

Living with Sickle Cell Disease means that every treatment comes with its own side effects. Today, we will focus on the ...