The disruption of endoplasmic reticulum (ER) homeostatic function ... the production of SASP components induces a high burden on the secretory pathway of ER, thereby requiring increased maintenance of ...

Accumulation of unfolded or misfolded proteins in the ER leads to endoplasmic reticulum stress (ERS) and activates the unfolded protein response (UPR) signaling pathway. The adaptive UPR has the ...

A recent research collaboration between multiple Japanese institutions has developed a technique to facilitate the study of protein biogenesis at the endoplasmic reticulum ... various fields related ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Live imaging of secretory cargoes is a ...

The NFL has announced its International Player Pathway (IPP) program Class of 2025 featuring 14 athletes representing 13 nations around the world, as the league continues to focus on creating more ...

When is the Path of Exile 2 release date? Path of Exile 2 has evolved from its initial role as effectively a large expansion to become its own full game, with completely new mechanics, classes ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic ... of harmful secretory pathway proteins," highlights ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic ... of harmful secretory pathway proteins," says Kadokura.

MHC Class I and MHC Class II Antigen Processing Pathways Antigen processing ... by spliceosomes and then directed into the endoplasmic reticulum (ER) through transport associated protein (TAP ...

Path of Exile 2, while having all of these in spades, is all about your power. Smacking someone in the face with a mace is great, but smacking someone in the face with a mace with several passive ...