In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.
Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a ...
Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer ...
PD-L1 not only responds to the cGAS-STING pathway upon DNA damage, but also regulates cGAS-STING to induce inflammation. This ...
In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...
To examine this interferon-neuron pathway — known as an interferon-induced STAT1 signaling pathway — further and see whether prolonged signaling could impact behavior, Filiano and his ...
Social sentiment around Bitcoin has hit its lowest point in 2024, which could signal an incoming recovery above the $100,000 mark for the world’s largest cryptocurrency. Bitcoin's (BTC ...
hnRNPM/ELAVL1 specifically promote cGAS and RIG-I signaling without affecting TLR or IFNAR pathways. In this study, we found that hnRNPM promotes the phosphorylation of IRF3 and expression of type I ...