Some of the included studies did not report data on all outcomes, and for these, we were not able to compare all the SGLT-2 inhibitors against each other. For example, the Seino et al21 trial with the ...

SGLT2 inhibitors are a new family of agents, which occlude the path of SGLT2 glucose reabsorption and cause glucosuria. Efficacy of SGLT2 inhibitors includes reduction of HbA1c, fasting and ...

The following is a summary of “Impact of sodium-glucose cotransporter 2 inhibitors on catheter ablation for atrial fibrillation in heart failure patients without type-2 diabetes,” published in the ...

BCL-2 inhibitors, such as venetoclax (Venclexta) work by targeting the BCL-2 protein, which plays a key role in preventing ...

USA: A recent editorial published in the Journal of Cardiothoracic and Vascular Anesthesia highlights the growing clinical applications of sodium-glucose cotransporter-2 (SGLT2) inhibitors. The first ...

The advent of immunotherapy based on immune checkpoint inhibitors has improved the treatment of advanced hepatocellular ...

Interline Therapeutics Inc. has synthesized receptor-interacting serine/threonine-protein kinase 2 (RIPK2; RIP-2) inhibitors reported to be useful for the treatment of inflammatory bowel disease (IBD) ...

These diseases can be congenital or acquired, for example, diabetes and phenylketonuria ... Here authors describe sulfonamide-based inhibitors and synthetic substrates, then apply to multiple ...

Glucose, also commonly called blood sugar, is the main source of energy for the body. Diabetes is a disease where your blood ...

"The NTRK inhibitor example is an especially sad one because those drugs are so active," said McLeod, who was involved in the research with Diaceutics. "There are very few situations where that wouldn ...

DPP-4 inhibitors improve your blood sugar without making it drop too low alogliptin (Nesina), linagliptin (Tradjenta), saxagliptin (Onglyza), and sitagliptin (Januvia) glucagon-like peptides ...