As noted above, stellate cell activation is the central ... matrix protease activity play an important role in ECM remodeling accompanying fibrosing liver injury (see section on Extracellular ...

First, the large liver mass, via the reticuloendothelial function of the Kupffer cells, is thought to be capable of sequestering cytotoxic antibodies formed against the graft. The presence of a ...

Activation of Kupffer cells (liver-resident macrophages ... A notable focus of the review is the role of extracellular vesicles (EVs) in intercellular communication. These nanoscale particles ...

Kupffer cells (KCs) also contribute to this inflammation ... The review examines how alcohol metabolism affects liver function, focusing on the roles of oxidative stress and inflammation in ...

Discover how liver cancer evades the body's natural defenses and explore the link between fatty liver disease and increased ...

Both receptors are expressed by liver resident macrophages, Kupffer cells (KCs). Methods To determine the role of KCs and interactions with PRRs in NASH, mice were fed a methionine choline deficient ...

When you get an infection, your liver plays a role in fighting off germs. The organ has a large number of cells called phagocytes that detect and destroy viruses and bacteria, especially those ...