Researchers discovered that the mRNA modification m6A triggers rapid degradation, regulating protein production. This ...

University of Würzburg researchers identified a fast mRNA degradation mechanism driven by m6A modifications. This process ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

One of the most prestigious global awards, the Nobel Prize 2024, will be handed out to the winners today in Sweden’s ...

The Pew Charitable Trusts announced today the eight pairs of researchers who will make up its 2024 class of Innovation Fund investigators.

In eukaryotic cells—found in animals, plants, and fungi—protein synthesis involves more than the simple assembly of amino acids in ribosomes. Nearly one-third of all human proteins must be transported ...

Protein synthesis in eukaryotic cells--found in plants, animals, and fungi--involves more than just the straightforward ...

Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...

In cell-free protein synthesis, cells are ripped apart at very high pressure, making it possible to extract the components such as ribosomes needed for protein production. Then, cellular energy ...

This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...

It was previously clear that the ribosome must somehow find the right place on the right mRNA to begin protein synthesis. To me, this suggested a potentially very long search before the molecules ...

The researchers believe that by comprehending these basic mechanisms, new antibiotics that target these particular pathways ...