In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, ...

Presence of a protein-binding biomarker in a small cohort of adults with depression may be an indicator that suicidal ...

Homozygous familial hypercholesterolaemia affects approximately 30 000 individuals worldwide.1,2 Patients have untreated high ...

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D ...

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate ...

A research team has discovered how the 'Shethna protein II' protects the nitrogen-fixing enzyme nitrogenase from damage. The oxygen sensor protein could help to make nitrogenase usable in ...

EBP1 is low in Alzheimer’s disease brains, hinting at human relevance. “Our study suggests that … preservation of functional EBP1 could be a therapeutic strategy for AD,” the authors noted. The ...

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel ...

Researchers at EPFL have opened up a world of possibilities in the computational design of molecular interactions for ...