Cytoskeleton rearrangements promote formation of a giant structure called a GUVac that stops cells from dying when they become detached from the extracellular matrix.

"But having both a bilayer-forming lipid, which provides the basic structure for the cell membrane, and a non-bilayer-forming lipid, such as cholesterol, which adds stability, seems to be a ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jctc.4c00927. Energy function details, RosettaMP Ensemble run details ...