Our small molecule, OR-812, has the potential to offer IBD patients a novel oral medicine with a differentiated mechanism of action ... such as vedolizumab and ozanimod, less than half of patients ...

Orphagen Pharmaceuticals, Inc., a biotech company pioneering the screening, discovery, and development of small molecule ligands that modulate orphan or unexplored members of the nuclear receptor ...

Because we all instinctively know that one can't possibly survive (or barely survive) such a long fall. Long falls are just one type of mechanism of injury that is seen in emergency medicine.

Signoriello declares no conflicts of interest. Ozanimod is an approved treatment for relapsing forms of multiple sclerosis (RMS) that has been shown to reduce relapses, new brain lesions, and brain ...

What we now call the Brout-Englert-Higgs mechanism gives a mass to the W and Z when they interact with an invisible field, now called the “Higgs field”, which pervades the universe. Just after the big ...

Pre-arbitration mechanisms are dispute resolution/prevention steps embodied in contracts between parties providing for an attempt at amicable resolution of the dispute. Parties have to abide by these ...

While it's well known that sleep enhances cognitive performance, the underlying neural mechanisms, particularly those related to nonrapid eye movement (NREM) sleep, remain largely unexplored.

State Key Joint Laboratory of Environmental Simulation and Pollution Control, State Environmental Protection Key Laboratory of Atmospheric Ozone Pollution Control, College of Environmental Sciences ...

Such automatic and typically unconscious processes act as defense mechanisms, protecting and defending us from further distress while reducing our awareness of internal danger. Primitive and less ...