gut.bmj7d
Neurotensin—regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis
Small interfering RNA (siRNA) was purchased from Santa Cruz Biotechnology (Santa ... and normal subjects (n=9) were purchased from Origene (Rockville, Maryland, USA). Conversion of cDNA of RNA samples ...
eLife27d
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
MLN7243 was purchased from Selleckchem. On target plus Human CRBN siRNAs (51185) and non-targeting siRNA pool were purchased from Horizon Discovery. Myc-Flag-human TEADs (OriGene) and V5-ubiquitin ...
Morningstar27d
Wave Life Sciences Announces Submission of First Clinical Trial Application for WVE-007 (siRNA Targeting INHBE) in Obesity
WVE-007 is an investigational GalNAc-conjugated small interfering RNA (siRNA) designed to silence Inhibin βE (INHBE) gene expression, which would induce fat burning (lipolysis) to decrease body ...
Transfection Reagents & Equipment Market Global Outlook: Next-Gen Transfection Reagents Fuel Breakthroughs In Molecular Biology
The "Transfection Reagents & Equipment market by Product, by Method, by Application, by End-User, and By Region" report has been added to ResearchAndMarkets.com's offering. The global transfection ...
BioSpace27d
Wave Life Sciences Announces Submission of First Clinical Trial Application for WVE-007 (siRNA Targeting INHBE) in Obesity
WVE-007 is a novel approach for treating obesity and is designed to silence INHBE to achieve healthy, sustainable weight loss through fat burning, muscle maintenance and the potential for once or ...
The EMBO Journal13d
PlexinD1 is a driver and a therapeutic target in advanced prostate cancer
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aggressive prostate cancer (PCa) variants ...