sarco/endoplasmic reticulum calcium ATPase pump inhibition; 4) superoxide scavenging; 5) neuromuscular junction modulation; 6) calcium–myosin interactions. See text for details. Nitric oxide (NO); ...

Figure 1: a, Baseline in vivo tracings of left ventricular (LV) pressure (upper) and the first derivative of ventricular pressure (dP/dt; lower) for young and older mice in both groups. Figure 2 ...

† Most-abundant zymogen granule proteins. ‡ Different isoforms present in zymogen granules. § Validated by morphological studies after identification by mass spectrometry. As the molecular ...

For common substrate-binding ATPase proteins, such as proteases, helicases, motor proteins, etc., the ATPase mechanism and function are well defined. In stark contrast, Hsp90 performs various ...

This protein, found in high levels in both skeletal and cardiac myofibrils, was determined to be >1 MDa in size through analytic ultracentrifugation and gel electrophoresis, using a multimeric myosin ...

1 Key Laboratory of Obstetric and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Department of Radiology, West China Second University Hospital, Sichuan University, ...

Notch1 is expressed uniformly throughout the mouse endocardium during the initial stages of heart valve formation, yet it remains unclear how Notch signaling is activated specifically in the AVC ...

Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research ...

Randall Centre for Cell and Molecular Biophysics, and British Heart Foundation Centre of Research Excellence, King’s College London, London SE1 1UL, United Kingdom ...

Intracellular lipid transport can occur by flip‐flop from one side of a bilayer to the other, by vesicular trafficking, by lipid transfer proteins, or by diffusion within a bilayer 34. MAMs are hubs ...