Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada (C.S., K.J.R). Centre for Infection, Immunity ...

Alonso has received honoraria fees by participating in an advisory board and symposia for Tecnofarma and Sanofi. Mata has received a research grant from Amryt Pharma Plc. The other authors have ...

He, H.J., Cen, X.H., Liang, Y.J., Zhong, J.M., Deng, J.H. and Jiang, Y.J. (2025) Progress in the Regulation of Lipid Metabolism by the Orphan Nuclear Receptor Nur77. Journal of Biosciences and ...

The liver is a crucial metabolic organ essential for maintaining normal physiological functions, including detoxification, protein synthesis, lipid metabolism, bile secretion, and glucose regulation ...

3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), the primary therapy, lower LDL-C by enhancing LDLR expression, yet many FH-related mutations lack mechanistic understanding.

This cover highlights the article ZBTB48 is a priming factor regulating B-cell-specific CIITA expression by Grishma Rane, Dennis Kappei and colleagues. The study identifies how ZBTB48, represented as ...

However, antihypertensive therapies can have differential effects on central aortic pressures, despite similar effects on brachial BP. 28,29 In view of the disproportionate elevation of central aortic ...