On the battleground of the human body, microbes use every skill to mask, infiltrate, manipulate, and evade the immune radar.

Macrophages are intricately involved in the presentation of antigens to lymphocytes and in the subsequent removal of immune complexes. Therefore, pharmacologic manipulation of these cells may ...

The TRACeR I platform was incorporated into a humanized antibody fragment in a bispecific T-cell engager (BiTE) format. When ...

Northwestern Medicine scientists have developed a method for identifying reactive cysteines on peptide antigens within the ...

This paper presents the important discovery that lipid metabolic imbalance caused by Snail, an EMT-related transcription factor, contributes to the acquisition of chemoresistance in cancer cells.

Sun, Y. , Cheng, X. and Pen, K. (2024) Clinical Value of Platelet-Related Parameters and Monocyte Counts in Patients with ...

No single clinical characteristic at presentation can be used to distinguish AtLP from benign or malignant lymphoid proliferation. Neither is any single criterion available to establish evolution ...

The authors imply that CD200, acting through CD200R, suppresses the tonic activation of macrophages and granulocytes ... will place the significance of the present findings in a clearer light.

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of ...

Background Obesity is associated with accumulation of macrophages in white adipose tissue (WAT), which contribute to the development of insulin resistance. Germ-free (GF) mice have reduced adiposity ...

These structures mark the corpses for recognition by the antigen-sampling receptor CLEC9A on dendritic cells.

Results Clinical-grade tolDCs established from patients with RA exhibit a typical tolerogenic phenotype of reduced costimulatory molecules, low production of proinflammatory cytokines and impaired ...