The strong allogeneic response to donor MHC molecules in transplantation and the weak response to tumor antigens ... the need for presentation of tumor peptides by self MHC class II molecules ...

Hypoxia contributes to cancer resistance to both standard therapies and immunotherapy. This work demonstrates that tumor ...

Study: Targeting peptide antigens using a multiallelic ... surface by class I major histocompatibility complex (MHC I) proteins. MHC 1 presentation is crucial to the immune response, as it allows ...

allowing the antigen to be produced inside of a host cell, leading to a cell-mediated immune response via the MHC I pathway. The plasmid DNA vaccine (above) carries the genetic code for a piece of ...