[66] One can postulate that antiproteases might protect the mammary gland from local proteolysis (caused by leukocytic or lysosomal proteases) and might prevent the proteolytic breakdown of milk ...

Cathepsin D (CTSD) is a lysosomal protease important for the degradation of various substrates, including disease-associated proteins like α-synuclein (a-syn), amyloid precursor protein (APP) and tau, ...

Chloroquine and hydroxychloroquine impede lysosomal activity and autophagy, leading to a decrease of antigen processing and presentation. They are also known to interfere with endosomal Toll-like ...

Moreover, caveolin is believed to take part in transport of newly synthesized cholesterol as well as free cholesterol released during lysosomal degradation of endocytized LDL from the endoplasmic ...