Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA.

The foot is a complex structure made up of 28 bones ... is an inflammatory form of arthritis caused by the accumulation of uric acid crystals in a joint. Gout symptoms occur in episodes, causing ...

One of those waste products is uric acid. It’s formed when your body breaks down purines, which are found in some foods and drinks. Most of the uric acid leaves your body when you pee ...

4c00599. Optimized gene sequence of wild-type RpALAS, sequences of primers used, multiple sequence alignment of key ALAS protein sequences, screening data from the linear search strategy with Arg 21 ...

In this study, we report a mild and convenient stereoretentive decarboxylative amidation of α,β-unsaturated carboxylic acids with easily procurable 1,4,2-dioxazol-5-ones, providing a practical ...

Suite of tools for deploying and training deep learning models using the JVM. Highlights include model import for keras, tensorflow, and onnx/pytorch, a modular and tiny c++ library for running math ...

Getting a case of acid reflux (heartburn) once in a while isn't unusual, but some people suffer from burning discomfort, bloating and belching almost every time they eat. About 20% of the population ...

While moving through this layer, cells start to lose their structure and characteristic and become more like the dead, flattened keratinocytes of the outermost layers. This skin layer also contains ...

Carboxylic acids have been shown to be good phosphate bioisosteres (Burke and Lee, 2003; Elliott et al., 2012). Yet phosphonic acids could potentially better-replicate cognate TOP1-DNA substrate ...

As the most relevant tetracarboxylic dianhydride, 5,5′-(1,1,3,3,5,5-hexamethyltrisiloxane-1,5-diyl)bisbicyclo[2.2.1]heptane-2,3-endo-dicarboxylic ... endo- from exo-structures when synthesizing ...