The DNA repair and replication pathways converge on a common final step in which the continuity of the repaired DNA strand is restored by DNA ligase, an enzyme that converts nicks into phosphodiester ...

This process is essential for DNA replication and is aberrantly enhanced ... links Cks1 with the Skp2 subunit of the SCF ubiquitin ligase. The cell's ability to self-reproduce is a fundamental ...

the helix structure is unwound special molecules break the weak hydrogen bonds between bases, which are holding the two strands together this process occurs at several locations on a DNA molecule ...