and the JNK kinase pathway. These pathways and their regulators and mediators are being intensely studied not only in osteoclast lineage cells but in a variety of other cells that express RANK.

Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, Jilin 130112, China School of Chemistry and Life Science, Changchun University of Technology, ...

Is there ongoing apoptosis of ß-cells, and, if so, is this caused by aberrant genetic programming or something bad that invades the ß-cell's microenvironment? Type 2 diabetes is characterized as ...

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Excessive mechanical loading downregulates FBXW7 to activate MKK7–JNK signalling, which stimulates chondrocyte senescence and consequently initiates and accelerates OA development. Inhibition of JNK ...

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Creation of all things; creation of Adam and Eve; temptation by Satan; Adam and Eve rebel against God and forfeit Garden of Eden. On that day, Adam and Eve, the father and mother of all mankind, chose ...

In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...

From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...