Researchers from Kumamoto University have identified a liver-derived protein, serine protease inhibitor A1 (SerpinA1), as a ...

By leveraging insights and tools, healthcare professionals can better address the intertwined challenges of obesity and T2D, ...

A model summarizing the insulin-signaling pathways in the liver, muscle, and pituitary of lean or DIO mice. Arrows indicate active signaling pathways, and an X over the arrow indicates blocked ...

A groundbreaking discovery has unveiled a promising avenue in diabetes research. Scientists have identified a novel enzyme, ...

The balance of protein health within cells, a process known as proteostasis, is critical for maintaining cellular ...

Investigators at the Helmholtz Institute have shown that inceptor, an inhibitor of the insulin signaling pathway, acted by binding insulin and targeting it for degradation. “Insulin was discovered 100 ...

What’s the secret behind calorie restriction’s health benefits? Meet LCA, a powerful molecule improving energy, muscle health ...

Breakthrough Therapy Designation granted based on key positive data from the Phase 2b (RIZE) study and current unmet medical need in congenital ...

Discover the significance of C. elegans in biological research, from Nobel Prize-winning discoveries to insights into gene ...

This important study reveals a critical role of the transcription factor NR2F2 in mouse fetal Leydig cell (FLC) differentiation. With elegantly carried out experiments, the authors provide compelling ...