Her team recently developed a small nanocarrier that actively delivers a poly (ADP-ribose) polymerase (PARP) inhibitor and a ...

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

Collaboration, they realized, was the only way to unlock these ancient interactions. "We knew that DNA was in close proximity to the magnesium-rich polyP condensates in cells, but we were totally ...

An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.

Scientists say they have recovered the oldest known Homo sapiens DNA from human remains found ... although that interaction did not necessarily happen in the same place. Scientists have known ...

The vulnerability, which Microsoft has now remediated, put 400 million users of Office 365 at risk of a 2FA bypass attack requiring no user interaction, triggering no alerts and only taking an ...

The second group includes hydrophobic interactions between drugs and nanocarriers (e.g., polymeric micelles from amphiphilic block copolymers). Polymeric nanocarriers in the third group include ...

The researchers cataloged the segments of Neanderthal DNA in each person’s genome, then compared them to see where those segments appeared and how that changed over time and distance.

Cephalexin has interactions with some other drugs and certain supplements. Examples include metformin and warfarin. Cephalexin is prescribed for treating certain bacterial infections in adults.