Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the ...
A new study from EMBL Barcelona researchers shows that metabolic activities selectively modulate the segmentation clock, ...
In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of ...
Lactylation is a reversible, covalent, post-translational modification of proteins. It happens exclusively on lysine residues, where it influences protein structure, stability, localization, and ...
By Winston Cho, Katie Kilkenny Surfacing from the ashes of Los Angeles’ raging wildfires is a plea from local entertainment industry folk gutted by the blazes: Bring production back to the region.
Despite the recent trend for laptops as the go-to music production tool, for some setups, you'll be better off with one of the best PCs for music production. A desktop machine will typically be more ...
NEW DELHI, Jan 16 (Reuters) - India will be the global production hub for Suzuki Motor's electric cars and it plans to export the vehicles back to Japan as well as other markets, such as Europe ...
By thoroughly analyzing GBM glycolysis, this study seeks to ... On the other hand, lactate-induced TME acidification inhibits CD8 T cell proliferation, cytokine production, and cytotoxic function.
Manipulations that curtail lactate generation or impede glycolysis tend to reduce the incidence of Kla, conversely, those that augment lactate production or stimulate glycolysis promote such ...
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical studies have implicated macrophage-mediated immune tolerance. Hence, pathways ...