The close correlation between AMPK activity and glucose transport suggests that these metabolic stressors use the same AMPK-dependent signaling pathway leading to accelerated glucose transport ...

Figure 1. Tumor suppressing pathways of LKB1. The LKB1-AMPK-mTOR pathway suppresses tumor development. LKB1-AMPK disrupt mTOR activity leading to decreased survival and proliferation while ...

The researchers found that overactivating AMPK in mice, either by using AMPK agonists or methods such as glucose depletion during Yersinia infection, can worsen the severity of the infection.

Scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation.