The Norman Lab aims to combine large-scale functional genomics experiments with computational modeling to enable rational engineering of cell state. Our primary model system is the fibroblast, a ...

Cardiovascular disease continues to lead as the primary cause of death across the globe, taking millions of lives every year.

Mesenchymal stem cells (MSCs) are fibroblast-like cells that can develop ... Finally, using a mouse model of graft-versus-host disease (GVHD) and MSCs from mice deficient in iNOS or the IFNγ ...