Peptides, as versatile biological molecules, have garnered significant attention in scientific research due to their ...

1 Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China 2 Department of Pancreatic Surgery, West China ...

Fibroblast-specific Tcf21 gene–deleted mice demonstrate ... sustained TCF21 expression prevents the induction of genes associated with fibrosis and ECM (extracellular matrix) organization.

Shanghai Key Laboratory of Orthopaedic Implant, Department of Orthopaedics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China ...

The tumor stroma is a tissue composed primarily of extracellular matrix, fibroblasts, immune cells, and vasculature. Its structure and functions, such as nutrient support and waste removal, are ...

Human lung fibroblasts stimulated with TGF-β1 to detect extracellular collagen I (pink), alpha-smooth muscle actin (α-SMA) (green), and cell nuclei (blue) as a measure of matrix production and ...

Introduction: After a myocardial infarction (MI), cardiac fibroblasts are activated to deposit extracellular matrix that while prevents acute cardiac rupture in the short-term, causes long-term ...

Fibroblasts are specialized cells in connective tissues that play an important role in wound healing and tissue repair. They produce and organize the so-called extracellular matrix, a network of ...

This study provides abundant valuable scRNA-Seq data that profiles fibroblasts involved in myocardium and coronary vasculature development. However, the evidence supporting the authors' claims is ...