Longevity Breakthrough: New Protein Discovery Could Be the Key to Healthier Aging
New research found that the protein MANF helps cells manage toxic protein clumps, improving cellular health and potentially ...
Daily3d
Breaking News: NMC Finalises NEET 2025 Syllabus, Check Details
Finalising the syllabus for the National Eligibility-Entrance Test Undergraduate (NEET-UG) 2025 examination, the ...
ahajournals.org28d
Neuroprotective Potential of Nitroglycerin in Ischemic Stroke: Insights into Neural Glucose Metabolism and Endoplasmic Reticulum Stress Inhibition
mRNA and protein expression of key molecules of hyperglycolysis, gluconeogenesis, endoplasmic reticulum stress as well as signaling ... 14 Positive TUNEL staining was detected using a fluorescence ...
GitHub25d
endoplasmic-reticulum
A Julia package to detect contacts below the precision of a superresolution microscope between 2 subcellular organelles in 2-channel superresolution (STED) microscopy.
eLife19h
A fat-2(wa17) suppressor screen in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency
This study investigates the fundamental role of polyunsaturated fatty acids (PUFAs) in membrane biology, using a unique model to perform a thorough genetic screen that highlights that PUFA synthesis ...
Detecting problems during protein synthesis with a firefly luciferase-based reporter
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the ...
Science Daily9d
A breakthrough tool for detecting problems during protein synthesis
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
eLife23d
Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis
This valuable study reports the first characterization of the CG14545 gene in Drosophila melanogaster, which the authors name "Sakura." Acting during germline stem cell fate and differentiation, ...
The EMBO Journal10d
RudLOV is an optically synchronized cargo transport method revealing unexpected effects of dynasore
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Live imaging of secretory cargoes is a ...
The EMBO Journal21d
Gpr54 deletion accelerates hair cycle and hair regeneration
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. GPR54, or KiSS-1R (Kisspeptin receptor), is ...