to the activated DRs to form a complex known as the death-induced signaling complex (DISC). In this context, caspase-8 then self-cleaves; its DED remains associated with DISC, whereas the ...
Their findings highlight the complex's ability to inhibit AR signaling and induce cell death in prostate cancer ... for dihydrotestosterone (DHT)-induced cell proliferation. Moreover, 5-H-Y ...
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