Each cell in our body experiences up to tens of thousands of DNA-damaging events per day, primarily from routine cellular maintenance or exposure to toxins in our environment. Despite the high ...

DNA repair: A look inside the cell's 'repair café'. ScienceDaily . Retrieved December 16, 2024 from www.sciencedaily.com / releases / 2024 / 11 / 241121115648.htm ...

But, a rigorous system of checks and balances is in place through the DNA repair machinery. The errors that slip through the cracks may sometimes be associated with disease, but they are also a ...

Northwestern Medicine investigators have discovered new molecular mechanisms underlying DNA repair dysregulation in prostate ...

To study DSB repair using this system, researchers treat cells with a dose of IR high enough so that the genomic DNA is shattered, leaving no intact chromosomal bands. Cells are then allowed time ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

Ilya Finkelstein’s research focuses on improving gene editing, understanding DNA repair and finding disease treatments.

The Shu complex, it turns out, may act as a backup system for BRCA2, a well-known protein that when mutated may lead to breast and endometrial/uterine cancer. SWSAP1-SWS1 helps repair broken DNA ...