New research reveals that centromeres, which are responsible for proper cell division, can rapidly reorganize over short time ...

New research reveals that centromeres, which are responsible for proper cell division, can rapidly reorganize over short time ...

Each chromosome has two arms, named p and q. These two arms are joined at a structure called the centromere. A translocation chromosome mutation can be of two types — reciprocal and Robertsonian.

Using a similar bioinformatics approach, we next screened for Loss of Function (LoF) variants in the inner kinetochore constitutive centromere associated network (CCAN). We show how six LoF variants ...

Biologists in Europe and the U.S. have pinpointed a secret that powers the human body’s gene replicating ability. These areas, called centromeres, are responsible for billions and billions of perfect ...

Our results show that the point centromere is the basic unit of holocentric organization in support of the classical polycentric model for holocentromeres, and provide a mechanistic basis for ...