In what they've confirmed as the largest study looking at the effects of diet on rates of colon cancer, researchers in the UK ...

State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology (P.Z., X.Y., X.Z., Y.L., X.F., Z.Y., J.Z., X.X., L.L., H.H.), Tangdu Hospital ...

(6) Mitochondria-associated membranes (MAMs), the contact sites between mitochondria and ER, are a central hub for Ca2+ signaling, apoptosis ... Concentrated calcium within microdomains maximizes ...

Breast calcifications are small calcium deposits that develop in breast tissue. They are very common and are usually benign (noncancerous). In some cases, certain types of breast calcifications ...

This research enhances our understanding of βAR signaling and its implications for heart health. It highlights the potential of targeting βAR pathways for developing novel therapies for heart ...

Physiological roles of cell competition in vertebrates and the universal mechanisms regulating diverse cell competition are unknown. Here, authors show that Foxo3-mediated physiological cell ...

Help Register Login Login Hi, %{firstName}% Hi, %{firstName}% Games Car rental The majority of older adults shouldn’t rely on calcium and vitamin D supplements to prevent falls and fractures, ...

2000). Overall, maintaining cellular homeostasis involves a complex balance between increasing MitCa 2+ to meet cellular energy demands and minimizing the risk of mitochondrial calcium overload, a ...

How frequent is this problem? On the one hand, nearly 12 million patients have angina and based on the COURAGE trial (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation), 42% ...

These are deposits of calcium, fats, and abnormal inflammatory cells that clog the arteries and reduce blood flow. This means that if you have calcium deposits in your coronary arteries, you have at ...

The results of the current study identify for the first time an effective pharmacological means (i.e., calcium channel blockers) to inhibit pancreatic β-cell expression of proapoptotic TXNIP ...

2014) and in conditional knock-out mouse (Simon et al., 2004). Cellular calcium homeostasis is intimately dependent on functional mitochondria. Therefore, frataxin overexpression in 3T3-L1 adipocytes ...