We have, therefore, developed a BAAT knockout mouse in our lab that lacks these taurine- and glycine-conjugated bile acids. By introducing MCBAs to the guts of these BAAT knockout mice ...

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors. It has ...

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors.

non-toxic increases in bile acid levels can improve metabolic disorders. Dr. Jae Man Lee, then a graduate student in the Program in Developmental Biology in Moore's laboratory, first proposed ...

Salk scientists link bile acids and immune cell performance in liver cancer, finding that supplementing the bile acid UDCA—already a current treatment for liver disease—and inhibiting bile ...