Dawn of Justice kept one side of the monstrous Doomsday ambiguous, but the TV series Superman & Lois provided a clear answer.
Superman villain Metallo once got the best of Batman by used an artificially engineered version of Kryptonite, designed to target human physiology rather than Kryptonian. Metallo's "Slow ...
McFarlane even crafted some Platinum Versions for the wave with the False God Superman statue figure as well as an Armored Batman, which came with a Kryptonite Spear and slightly tinted deco.