Two newly identified disease-causing genes, known as Bzw2 and Eif5a2, have been implicated in early prostate cancer ...

Funded by Prostate Cancer UK, the ICR team focused on genes involved in the PI3K-AKT pathway, which is frequently mutated in ...

The study revealed that NAM activates CK1-mediated β-catenin signaling, while PN stimulates the AKT pathway, both of which are critical for MuSC proliferation and differentiation. Custom high ...

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are being used as reagents to define the role of these ...

The addition of Truqap to standard-of-care therapy improved radiographic progression-free survival in patients with ...