ATAC-seq and RNA-seq analysis reveals that AurA inhibition restricts chromatin accessibility of genes associated with inflammatory pathways such as JAK-STAT ... AurA inhibition reduced the activation ...
It is noteworthy that the redox-mediated reprogramming of signalling pathways is not limited to PI3k/Akt pathway. A detailed review of the concept can be found elsewhere (Vujovic et al., 2023). Figure ...
Figure. Schematic diagram depicting signaling pathways for regulation of phospho-Ser473-Akt activity cell survival by PHLPP-1. Site-specific dephosphorylation of Ser473-Akt, but not Thr308-Akt by ...
Results: RAGE upon activation by its ligands enhances downstream signaling pathways, contributing to breast cancer cells migration, growth, angiogenesis, metastasis, and drug resistance. In addition, ...
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