LIN treatment decreased the expression of muscle RING-finger protein-1 (MuRF1) and Atrogin1(MAFbx) in muscle, and the activation of insulin-like growth factor-1 (IGF-1)/protein kinase B (Akt)/forkhead ...

Figure. Schematic diagram depicting signaling pathways for regulation of phospho-Ser473-Akt activity cell survival by PHLPP-1. Site-specific dephosphorylation of Ser473-Akt, but not Thr308-Akt by ...

Diabetes. 2008;57(7):1805-1813. In conclusion, our findings suggest that the increase of glucose uptake by skeletal muscle may contribute to better glycemic control observed in Ad-36-induced ...

Together with its dominant immunological and bone remodeling involvement, RRO axis, comprising of receptor activator of nuclear factor-κB (RANK), RANK ligand (RANKL), and osteoprotegerin (OPG) ...

Cover picture: Inspired by the Review by Jung-Soon Mo, Hyun Woo Park and Kun-Liang Guan. Illustrated by Sandra Krahl.

Conventional criteria for monitoring the cytotoxic therapy of malignant tumors are defined by the therapy-induced reduction of tumor size, generally measured by radiologic techniques. The World Health ...